2015年11月8日星期日

Warning Signs of Lupus Nephritis

Lupus Nephritis is a serious complication of systemic lupus erythematosus (SLE). In most cases, it develops in the early course of SLE, but it can occur late. Delayed Lupus Nephritis is more common than previously recognized. As Lupus Nephritis is the most common death cause of the patients with SLE and the mortality is higher for lupus patients who develop nephritis than those who do not, it is very important for the patients with SLE to keep on the lookout for the signs of Lupus Nephritis.

1. Asymptomatic proteinuria or/and hematuria: Asymptomatic proteinuria or/and hematuria are very common among the patients with Lupus Nephritis. The proteinuria (urine protein<2.5 grams per day) and hematuria are mainly mild-moderate

2. Acute Nephritis Syndrome: This type is rare. The symptoms of Acute Nephritis Syndrome are very similar to Acute Nephritis caused by streplococcal infection.

3. Rapidly Progressive Nephritis Syndrome: It is rare type of Lupus Nephritis among the patients with SLE. Clinically, it is very similar to Rapidly Progressive Glomerulonephritis. Rapidly Progressive Nephritis Syndrome is bad. In about 3 months, the creatine level may double and it may develop into Uremia in several months and even weeks.

4. Nephrotic Syndrome: Nephrotic Syndrome is very common for the patients with Lupus Nephritis and covers about 2/3 of the total population. However, most patients do not have hyperlipidemia. Untreated effectively, it will progress into Uremia in 2 to 3 years. This pathological type of Lupus Nephritis is often mistaken for Primary Nephrotic Syndrome so the patients need to have an accurate diagnosis before receiving treatment.

5. Chronic Nephritis Syndrome: If the patients with SLE develop Chronic Nephritis Syndrome, they will have persistent proteinuria, hematuria, edema, high blood pressure, anemia and renal insufficiency and so on. The disease course can last for a long time and develops into Uremia if without treatment in time.

6. In rare cases of Lupus Nephritis, the patients may have the symptoms of Tubular Nephritis and Interstitial Nephritis. The specific gravity and/or osmotic pressure decreases and the urine output increases at night along with electrolyte disturbance and other symptoms.

As the prognosis associated with Lupus Nephritis is poor, it is very important for them to receive effective treatment in time if they have the above symptom.

If you want to know more information about other aspects on Lupus Nephritis treatment, prognosis, daily care and so on, you can email to kidney-treatment@hotmail.com .

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