2015年11月23日星期一

Common Symptoms of Chronic Renal Failure

In Chronic Renal Failure, with the chronic progression of the disease, the nephron is extensively damaged. As a result, the kidneys lose the normal filtration function in excreting metabolic products and excessive water, which then lead to a series of clinical symptoms.

1. Digestive system

Digestive function disorder is usually the early and common symptom of Chronic Renal Failure. The patients have poor appetite, nausea, vomit, abdominal distention or frequent diarrhea. In severe case, they will have oral ulcer, ammoniacal odour in mouth, upper gastrointestinal hemorrhage and intense thirst.

2. Blood system

Anemia is a common symptom in Chronic Renal Failure and usually the hemoglobin level is only 5~6g/dl. For anemia, the number of platelet declines so the patients often have hemorrhagic tendency and white blood cells abnormality.

3. Cardiovascular system

Hypertension has 70~100% of incidence among in Chronic Renal Failure and is the most common death cause for the patients with Chronic Renal Failure. As many patients do not have symptoms in the early period, they often neglect its treatment. Consequently, the form and function of heart will change a lot over time thus leading to atherosclerosis, left ventricular hypertrophy, heart failure, pericarditis and even cerebral hemorrhage.

4. Nerve system and muscle

In the early period of Chronic Renal Failure, the patients usually have headache, dizziness, fatigue, insomnia, inattention and also some patients may have sexual dysfunction. In the late period, the patients usually have peripheral neuropathy, dysphoria, and muscular tremors and so on. With the disease progression, the patients will have systemic numbness, fatigue and so on.

5. Bone disease

In uremic period, some patients’ bone will change abnormally, which can lead to fracture, bone ache and so on.

6. Respiratory system

When the patients with Chronic Renal Failure suffer from acidosis, they often have deep breath and even bronchitis, pleuritis. Therefore, the patients usually have dry cough and ammoniacal odour in smell.

7. Skin disease

As the kidneys can not discharge the metabolic products, the urea cream will deposit on skin and also the surface of skin will have dander, itching and so on.

8. Endocrine disorder

For endocrine disorder, the kidneys can not secrete hormone normally.


As Chronic Renal Failure can lead to so many symptoms, it is very important for the patients to receive treatment as early as possible. If you want to know other aspects of Chronic Renal Failure like treatment, diet and so on, you can email to kidney-treatment@hotmial.com or consult us on line.

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