In Chronic Renal Failure, with the chronic progression of the disease, the nephron is extensively damaged. As a result, the kidneys lose the normal filtration function in excreting metabolic products and excessive water, which then lead to a series of clinical symptoms.
1. Digestive system
Digestive function disorder is usually the early and common symptom of
Chronic Renal Failure. The patients have poor appetite, nausea, vomit, abdominal
distention or frequent diarrhea. In severe case, they will have oral ulcer,
ammoniacal odour in mouth, upper gastrointestinal hemorrhage and intense
2. Blood system
Anemia is a common symptom in Chronic Renal Failure and usually the
hemoglobin level is only 5~6g/dl. For anemia, the number of platelet declines so
the patients often have hemorrhagic tendency and white blood cells
3. Cardiovascular system
Hypertension has 70~100% of incidence among in Chronic Renal Failure and is
the most common death cause for the patients with Chronic Renal Failure. As many
patients do not have symptoms in the early period, they often neglect its
treatment. Consequently, the form and function of heart will change a lot over
time thus leading to atherosclerosis, left ventricular hypertrophy, heart
failure, pericarditis and even cerebral hemorrhage.
4. Nerve system and muscle
In the early period of Chronic Renal Failure, the patients usually have
headache, dizziness, fatigue, insomnia, inattention and also some patients may
have sexual dysfunction. In the late period, the patients usually have
peripheral neuropathy, dysphoria, and muscular tremors and so on. With the
disease progression, the patients will have systemic numbness, fatigue and so
5. Bone disease
In uremic period, some patients’ bone will change abnormally, which can lead
to fracture, bone ache and so on.
6. Respiratory system
When the patients with Chronic Renal Failure suffer from acidosis, they often
have deep breath and even bronchitis, pleuritis. Therefore, the patients usually
have dry cough and ammoniacal odour in smell.
7. Skin disease
As the kidneys can not discharge the metabolic products, the urea cream will
deposit on skin and also the surface of skin will have dander, itching and so
8. Endocrine disorder
For endocrine disorder, the kidneys can not secrete hormone normally.
As Chronic Renal Failure can lead to so many symptoms, it is very important
for the patients to receive treatment as early as possible. If you want to know
other aspects of Chronic Renal Failure like treatment, diet and so on, you can
email to firstname.lastname@example.org or consult us on line.