Polycystic Kidney Disease (PKD) is caused by abnormal gene. In present medicine area, there is no cure for the disease. However, if they can receive treatment in time, it is possible for them to avoid Renal Failure. The conservative therapies for Polycystic Kidney Disease (PKD) are as follows:
In the early stage of Polycystic Kidney Disease (PKD), the patients do not
have abnormal symptoms. Usually, it is inspected in physical exam or check for
other diseases. At that time, the doctors just tell their patients there is no
treatment for the disease at all. As a result, the cysts will continuously
enlarge. When they enlarge to some extent, they will lead to some clinical
symptoms like high blood pressure, back pain, urinary infection and so on. Then
when going to see a doctor for the above symptoms, they just prescribe them some
medicines for them to lowering blood pressure, remitting pain and so on.
However, those medicines can not prevent the renal function decline at all.
In severe cases of Polycystic Kidney Disease, surgery often recommended to
the patients. However, as there are numerous cysts on kidneys, it is impossible
for them to remove them completely. Moreover, after the big ones are removed,
the small cysts will enlarge very soon for more available space. Also surgery
can bring much trauma to kidneys. After surgery, the renal function has obvious
More than 50% of the patients with Polycystic Kidney Disease (PKD) develop
End Stage Renal Failure. At that time, dialysis or Kidney Transplant are
necessary for them to preserve their life. As for dialysis, it can only remove
the micromolecule substances from blood, but the macromolecular and
mild-molecular substances are still remain in blood and cause further damage to
body. Also, our kidneys can secrete renin a hormone in regulating blood
pressure. However, dialysis can not meet this requirement at all.
In terms of Kidney Transplant, the transplanted kidneys can take over the
whole function of the native kidneys. However, as the kidney source is rare many
patients may die during their long waiting. In addition, even if Kidney
Transplant is successful, they have to depend on immunosuppressive drugs to
prevent the severe rejection reaction in the rest of their life. In some cases
of rejection reaction and complications after Kidney Transplant, the patients
may lose their renal function of transplanted kidneys very soon.
Therefore, for the patients with Polycystic Kidney Disease (PKD), the key to
prevent their renal function decline is to block and shrink their enlarged cysts
as well as repair their impaired nephrons. In this way, they will be able to
avoid Renal Failure.