There are a lot of symptoms present if one gets Nephrotic Syndrome, of all the symptoms swelling is the most common and noticeable outcome.
Various reasons can result in swelling and long term swelling can also lead
to many diseases, bringing great misery to patients. This condition can be
caused by a multitude factors.
1. Proteinuria will trigger swelling of Nephrotic Syndrome.
Clinical study shows that proteinuria is the direct reason that causes the
swelling for Nephrotic Syndrome patients. The protein concentrations will
decrease when the mass proteinuria presents. At this time, plasma colloidal
osmotic pressure (COP) will decrease, which will cause the water proportion in
the blood higher than that in tissues. Therefore, water in the blood will
permeate into the tissues and with the large amount of water in the tissues,
2. Swelling itself will aggravate the swelling of Nephrotic Syndrome
Swelling will become severer if large amount of proteinuria is not controlled
because swelling formed in the stage of mass proteinuria and body cavity
effusion itself can make swelling severer. Swelling and body cavity effusion
lead to the blood insufficiency for effective blood circulation, which will make
the increase of aldosterone. The increase of aldosterone leads to retention of
water and sodium, which will aggravate the swelling. Severer swelling will
influence the vital signs and threaten our lives.
So it's far from enough to use diuretic only to treat swelling of Nephrotic
Syndrome, which can not effectively treat it. What we really need is to block
the process of fibrosis, repair the intrinsic cells of the damaged kidney and
recover the inherent organization and structure of the kidneys so as to
effectively treat the disease.
Experts pointed that it's better to use the combining method of
dietarytherapy and physiotherapy but the drug intervention when swelling
presents which will cause less side effects comparatively. Moreover, it is
necessary for patients with swelling to do proper exercise.