2015年11月28日星期六

How Do You Get Diabetic Nephropathy

Diabetic Nephropathy is a serious complication of Diabetes. It is one of common death causes for the patients with Diabetes. In the United States, nearly 4000 patients with Diabetes die of Diabetic Nephropathy and patients with Diabetic Nephropathy on dialysis covers about 1/4 of the total population. Therefore, the patients with Diabetes should know how they get Diabetic Nephropathy so as to take prevention in time.

Diabetes can lead to systemic microangiopathy. As glomeruli responsible for filtrating blood and excreting excessive fluid and wastes in kidneys are composed of masses of capillaries, kidneys are very likely to be influenced by microangiopathy. If the patients have a poor control of their blood pressure, kidneys will have pathological changes very easily. The glomerular basilar membrane becomes thick and also hyaline deposits in membrane thus causing the capillaries’ permeability to increase. The renal microangiopathy can lead to diffusive or segmental glomerular sclerosis. It is the basic pathogenesis of Diabetic Nephropathy.

Microangiopathy in Diabetes can cause renal ischemia and anoxia resulting in the increased blood viscosity. As a result, the pressure in glomerular capillaries increase and the resistance in arteries and afferent arteriole become higher. Therefore, the ultrafiltration pressure rises. As the glomerular capillaries and small arteries are damaged, the patients will have proteinuria, edema and Renal Failure, high blood pressure and so on.


Diabetic Nephropathy is very common among the patients with more than 10~15 years of Diabetes. However, patients do not know much about this disease so most of them do not receive treatment until they have a large amount of protein in urine. In that case, they have missed the best therapeutic opportunity and it is very difficult to reverse the renal function. Therefore, the patients with Diabetes, especially those with a long disease history, they should go to do renal test, urine test and blood test regularly so as to find if they have renal injury in the first time. If you are or your loved ones are Diabetes sufferers and want to know more about the treatments and prevention of Diabetic Nephropathy, please consult us on line or email to kidney-treatment@hotmail.com.

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