Significance of HBALC Test in Diabetes

In clinic, the levels of fasting blood glucose, postprandial blood glucose and HBALC are used to monitor the change in blood glucose. The levels of fasting blood glucose and postprandial blood only can reflect the instant blood glucose level so it can not reflect the blood glucose change in a long period. Compared with fasting blood glucose and postprandial blood glucose levels, HBALC has more significance in monitoring blood glucose.

After the blood glucose level rises, it will combine with the hemoglobin forming HBALC. Once they combine, they will not separate easily, but will disappear with the metabolism of red blood cells. As the life expectancy of red blood cells is 120 days, HBALC can reflect the blood glucose level in about two months.

In Diabetes, the most important thing is to control complications. If the persons can control blood glucose within target level, the incidence of complications will decline greatly. If the HBALC level is too high in blood, they will affect the affinity of red blood cells for oxgen resulting in tissues and cells anoxia and giving rise to hyperlipidemia. Moreover, it also can thicken the glomerular basilar membrane thus resulting in Diabetic Nephropathy. The researches conducted by Medical College in Cambridge University show that once HBALC rises by 1%, the chance of developing Coronary and Heart Diseases will increase by 15~18% and death rate increases by 20~30%. ADA suggests that the HBALC should keep below 7% and IDF suggests 6.5%. For the patients with Diabetes, if the HBALC keeps below 7%, it proves that their blood glucose keeps stable. However, if it is above 8%, they should control their blood glucose more strictly and adjust their treatment schedule immediately.

Therefore, the patients with Diabetes should attaché more importance to controlling HBALC so as to reduce the incidence of complications.

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