Can Lupus Cause Chronic Kidney Disease

Lupus also known as systemic lupus erythemotosus (SLE) is a common medical condition, especially in young women. It is a chronic inflammatory disease which can cause damage to multiple systems such as skin, heart, lung, kidneys etc. In fact, approximately 100% of the patients with lupus have renal injury. If left untreated, it is very likely to cause Chronic Kidney Disease.

Lupus is an autoimmune disease and it can cause immune injury to the systems of the whole body. In healthy condition, the immune system can produce antibodies to fight against bacteria and other infections. However, the lupus can prevent the antibodies from functioning normally. In lupus, the antibodies can not tell from the foreign pathological substances and the body’s own healthy cells and tissues. As a result, the antibodies attack the kidneys resulting in immune complexes to deposit in glomerular capillary subepithelial cells. The immune complexes attract inflammatory factors ceaselessly thus causing inflammation of kidneys. If the inflammation is not inhibited, it will cause renal injury progressively and chronically thus leading to Chronic Kidney Disease. In clinic, the paitents will present a series of symptoms of Chronic Kidney Disease.
To stop progression of Chronic Kidney Disease in lupus, the patients should to take proper treatment which can suppress the inflammation and clear up immune complexes as well as restore the injured epithelial cells.
Here the latest therapy-immunotherapy is suggested to the patients with Chronic Kidney Disease caused by lupus.

In the early stage of Chronic Kidney Disease due to lupus, if the patients can receive the above systemic treatment, they will be certainly able to avoid developing into Renal Failure.

However, not all patients with lupus will develop Chronic Kidney Disease. If you want to know if you are at risk of Chronic Kidney Disease, you can consult our experts on line. After analyze your illness condition comprehensively, we will evaluate your risk of developing Chronic Kidney Disease.

Learn More: What are New Guidelines for Lupus Nephritis