Essential amino acid can not be synthetized by our body. We mainly obtain essential amino acid from protein. However, for the patients with chronic Renal Failure, they should limit the protein intake. Therefore, it is very important for them to increase the essential amino acid intake.
Amino acid includes essential amino acid and nonessential amino acid.
Nonessential amino acid can be synthetized by our own body so we do not have to
obtain them from food. Generally, the content of nonessential amino acid is high
in plant food like rice, beans and so on. After the amino acid is metabolized,
they will produce urine nitrogen, creatinine and other metabolic wastes. For the
patients with Chronic Renal Failure, they should limit the protein intake.
Therefore, the essential amino acid in their body decreases. However, the
nonessential amino acid increases relatively. The imbalanced proportion between
essential amino acid and nonessential acid can cause less protein to be
synthetized and more to be broken down. Therefore, the non-protein nitrogen
increases. Therefore, if the patients with Chronic Renal Failure can increase
the essential amino acid intake and keep a low protein diet at the same time, it
not only can increase the protein synthesis in body, but also can correct the
imbalanced proportion between essential amino acid and nonessential amino
Meanwhile, essential amino acid therapy along with low protein diet can
decrease the phosphorus intake greatly thus lowering blood phosphorus level and
correcting the metabolic disturbance of calcium and phosphorus. Histidine and
tyrosine are not essential amino acid to the healthy persons. However, for the
patients with Chronic Renal Failure, the precursor production of histidine
decreases leading to histidine insufficiency. Phenylalanine hydroxylase activity
declines so less tyrosine is produced thus leading to tyrosine insufficiency.
Therefore, histidine and tyrosine are also essential amino acid and they should
increase their supplement.