2014年12月18日星期四

Identification and diagnosis of nephrotic syndrome

Nephrotic syndrome (NS) for a variety of reasons, the addition of permeability of the glomerular basement membrane appears as proteinuria, hypoalbuminemia, height edema, hyperlipidemia in a clinical syndrome. How identification and diagnosis?

1. Allergic purpura nephritis

More occurs teenager has typical crazy purple skin often in the distal extremities symmetrically after visitas1-4semana occurs hematuria and (or) proteinuria.

2. Systemic lupus nephritis

More middle-aged women and adolescent immune examination showed a variety of autoantibodies, and multisystem damage occurs puade clear diagnosis.

3. The hepatitis B virus associated glomerulonephritis

More children and youth occurs major clinical proteinuria or NS common pathological type was membranous nephropathy, diagnosis is based on: ① serum HBV antigen-positive; ② suffering from glomerulonephritis, and exclusion of secondary glomerulonephritis; ③ renal biopsy found HBV antigens.

4. Diabetic nephropathy

More Mid happens, common in the course of 10 years old with diabetes. It can be found in the first urinary albumin excretion increased, then gradually became a massive proteinuria, NS. History of diabetes and useful features in the differential diagnosis of changes in the retina.

5. Renal amyloidosis degeneration

More occurs in middle age, renal amyloidosis degeneration is part of the involvement of multiple organs. Primary amyloidosis, mainly with the heart, kidneys, gastrointestinal tract (including language), skin and nerves; Secondary amyloidosis often secondary to chronic suppurative infection, tuberculosis, cancer and other diseases, mainly involving the kidneys, liver and spleen and other organs. Volume increases renal involvement, often NS. Renal amyloidosis often require renal biopsy.

6. More occurs in middle age, is more common in men, patients may have multiple myeloma clinical features, eg bone pain, monoclonal globulin serum and urine protein electrophoresis protein band M positive this week , plasma cells in the bone marrow show abnormal proliferation (cell nucleus occupies more than 15%), and accompanied by a qualitative change. Multiple myeloma involving the glomeruli can occur when NS. The characteristic features of differential diagnosis for myeloma.

These are identification and diagnosis of nephrotic syndrome, most seniors and youth occurs. If you propremas, please leave us a the messaging leave your phone number.

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