There are different types of Nephrotic Syndrome. The disease may be primary
or secondary. A secondary NS means that it results from another disease such as
cancer, HIV-infection or Diabetes. Treatment varies with specific cause.
Causes of Secondary NS
Diabetic Nephropathy. The disease is also called diabetic glomerulosclerosis.
This form of NS occurs only in Diabetics, and patients with the disorder usually
progress to end stage renal disease (ESRD).
Renal amyloidosis. In general, patients with the disease will develop NS in 3
to 5 years. The deposition of amyloid fibrils in the kidneys is associated with
B cell lymphomas and chronic inflammatory states such as rheumatoid
arthritis.
Lupus Nephritis
Systemic lupus erythematosis (SLE) can lead to mild to serious kidney
problems. About 20 to 50 percent of patients with the disease will develop
NS.
Purpura Nephritis
This disorder is common among adults. Almost all patients occur renal injury
and some people may develop NS.
Treatment of secondary NS
Secondary causes account for <10% of childhood cases but >50% of adult
cases.
In diabetes, metabolic control is the mainstay of treatment. In other
secondary causes of NS, specific treatment varies depending on the causative
illness, e.g. immunosuppressive therapy of a systemic disease, or Immunotherapy
for autoimmune renal diseases.
At present, Immunotherapy is the latestest treatment for secondary NS caused
by immunological diseases. With this new treatment, the overall immune system
can be regulated, so the symptoms will be eliminated and the root cause is
eradicated.
Besides, in order to reduce the incidence of secondary NS, people should pay
attention to prevent the primary disease. Once diagnosed with Nephrotic
Syndrome, patients should seek for treatment as early as possible to avoid
further kidney damage. If you need any help, send an email to
kidney-support@hotmail.com or call +86 311 8926-1580.