2015年5月23日星期六

Why do IgA Nephritis Patients Wake up with Swollen Hands and Face

Swollen hands and face could occur due to a number of reasons, but the most common reason is because of fluid retention in the affected part. The most common places for swelling are the hands, feet, arms, legs and ankles, etc. Why do people with IgA Nephritis experience swelling of the hands and face?

IgA Nephropathy is a silent disease that may go undetected for years, but the onset is often before the age of 40. It is caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli(tiny blood vessels, or capillaries) within the kidneys.

The glomeruli normally filter waste products and excessive fluid from the blood stream and send them to the bladder as urine. However, IgA deposits prevent this filtering process, leading to excessive fluid's trapped in the body's tissues.
Due to capillary damage or increased pressure, tiny blood vessels leak fluid into the surrounding tissue, the area will begin to become swollen.

Leaking capillaries will cause the kidneys to collect higher than normal amount of salt and water in order to compensate for the capillary fluid loss. As a result, there is increased blood circulation in the body. In turn, even more capillary leak into the around tissue, causing additional swelling- a vicious circle.

The condition is more serious if the swollen hands and face are coupled with a shortness of breath, unexplained weight gain or nausea. Any of these signs, combined with swelling of the hands and face, are a signal that IgA Nephritis has progressed to advanced stages.


To alleviate the swollen hands and face, reducing the salt consumption and having enough rest during the day are necessary. If the problem persists, IgA Nephritis patients need to seek for medical treatment as early as possible. Or, you can consult our online experts for free help.

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