Nephrotic Syndrome (NS) refers to a condition that often results from a number of diseases that cause inflammation of the filtering system of the kidneys, the glomeruli. Hence, large amount of protein leaks from the blood into the urine. NS can be caused due to malfunction of the immune system, which could result from a virus or autoimmune disorder such as systemic lupus erythematosus. The immune system produces infection-fighting proteins known as antibodies that attack of glomeruli. Other causes of the disease also include allergic reaction to insect bites.
Evidence has proven that NS is more likely to happen on persons with family
history or prior history of allergy. Actually, in many cases, the disease is
precipitated by a hypersensitive event, such as insect sting, ant bites, poison
ivy, and immunizations.
Besides, the most common causes of NS also include various kidney diseases,
systemic diseases, and infections.
1. Various nephropathies, or glomerulopathies
Among these diseases, glomerulonephritis (GN) occupies peak position among
kidney diseases that cause NS. The pathogenesis of various nephropathies causing
NS is associated with the problem in the body's immune system. Normally, immune
system protects the body against invade of foreign materials like a virus and
However, with an abnormal immune system, the kidneys may be damaged. The
immune system will mistakenly attack the kidneys' filters-glomeruli, causing
them to become inflamed.
2. Systemic diseases
Those diseases will effect many organs and systems in the body, one of which
being kidney. When the kidneys are affected, the damaged glomeruli will leak
proteins. These conditions include Diabetes, Henoch-Schonlein Purpura, multiple
Certain infections including malaria, hepatitis B and C, streptococcal throat
infection, syphilis, etc can also lead to NS.
As one of the largest kidney disease specialized hospital throughout the
world, patient's treatment for NS in Shijiazhuang Kidney Disease Hospital is
tailored specifically for each affected individual by highly experienced and
renowned kidney experts. They work together in teams, communicating and
collaborating at every stem, to be sure they receive the most advanced therapies
with no side effects. If you of your beloved one is diagnosed with NS, we're
here to help.