2015年5月9日星期六

Kidney Failure and Urinary Changes in Humans

Kidney Failure is a decrease in renal function that results in an accumulation of unwanted substances in the body. Healthy kidneys work as a filter that cleans the blood and as the organs to produce urine. When the kidneys can no longer perform their function efficiently, patients can develop many symptoms. What are the urinary changes in Renal Failure?

Urine Protein

Diminished renal reserve describes the early changes of kidney function. With a normal GFR and no symptoms, the only clinical finding is protein in the urine, which can be detected in a random urinalysis.

Decreased urine output

Normally, kidneys excrete metabolic wastes through urine. When the kidneys function abnormally, the rate of urine excretion reduces. In most cases, changes in urine output is the first signs recognized by most persons diagnosed with chronic kidney disease. If the failure becomes permanent then urine output will be almost zero.

Increased urination

Kidney damage characteristic of Kidney Failure can affect the way in which waste fluid is removed from the body. Patients with this disease often present frequent urination during the night. This is called nocturia.

Colorless and clear urine

As renal injury accumulates, the urine production becomes abnormal. People with CRF may experience brisk urine production, as the kidneys are unable to concentrate the urine as normal. In this case, the urine is typically nearly colorless and clear.


Symptoms of Kidney Failure can very from person to person. With failed kidney function, high levels of urea may build up in the blood, which can also result in foamy or bubbly urine, dark colored urine, blood in the urine, pressure or difficulty urinating.

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