2012年10月15日星期一

A New Approach to Treat Lupus Nephritis – Blood Purification


End-stage renal failure is the main cause of death in SLE patients. Kidneys are involved in all the SLE cases. About 50% patients have the symptoms of kidney damage such as protein in the urine, blood in the urine, swelling, high blood pressure, and elevated BUN and creatinine levels.

The conventional approach treatments
GCS and immunosuppressive drugs are the commonest medicines used to treat LN (lupus nephritis). In deed these medicines work well on alleviating the symptoms of LN but it is terrible that they cause the side effects.

Here are some of the side effects of GCS and immunosuppressive drugs:
1. The imbalance of fluid and electrolytes.
Long-term use of glucocorticoids will causes the imbalance of fluid and electrolytes such as swelling, low blood potassium, high blood pressure, sugar urine, appearance change, myasthemia and so on. In addition, children may have a delayed development.
2. Cause or aggravate infection.
GCS can restrain the immune system and is unable to fight against germs so a long-term use can cause or aggravate infection, which may cause serious infection especially for people with low immunity.
3. Cardiovascular disease
It can lead to water retention and elevated fat levels in the blood, causing high blood pressure and atherosclerosis.
4. Mental abnormality
GCS can lead to mental abnormality such as exciting, insomnia, and mood swings. In some cases, patients have the tendency to suicide.

Blood purification - Alternative Treatment in Kidney Disease Hospital
Lupus nephritis is not only a kidney disorder but also systemic disease involving many organs of the body that is closely related to complex and antibody. It is not a cure to restrain immune and inflammation response alone. After years’ experiments and clinical trials, blood purification is created and used to treat Lupus nephritis.
1. Plasma exchange
Remove plasma containing harmful substance and then infuse healthy plasma into the patients.
2. Blood-lipid purification
With techniques and equipment, remove the LDL out of the body to improve hyperlipemia and reduce the risk of developing cardiovascular diseases.
3. Cell Removal Therapy
It refers to remove the excessive white cells to reach a normal level of cells in the body.
4. Immunoadsorbent technique
When the blood containing harmful substances flow thorough special equipment and then the harmful substances will be absorbed by special substances called immunosorbent.
These advanced techniques reduce the sides effects caused by medicines and rapidly alleviate the symptoms.

Here are the advantages of blood purification
1, Protect kidneys and stop the harmful substances damaging kidneys.
2. Stop harmful substances damage other organs especially heart and brain to reduce the incidence of sudden death and brain disease.
3. Clean the internal environment for the application of other therapies and improve the effects of other medicines.
The treatment of lupus nephritis is important for the prognosis of lupus nephritis. Different approaches determine the different diagnosis and life span. In addition to the alleviation of symptoms, removing the complex is also very important. Blood purification has been a current treatment.
If you are diagnosed with lupus nephritis, you can email to renalhealth@hotmail.com, we are here to help you.

Learn More: Factors Affect the Prognosis of Lupus Nephritis

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