Steroid-resistant nephrotic syndrome refers to patients without urinary remission after 4 weeks of 60mg / m2 / day. Prednisone Protein in the urine is a typical sign of the disease. If patients do not respond to steroids, what's the other treatment should they have?
Steroid-resistant nephrotic syndrome with protein in the urine
Steroids is the choice of first-line treatment for nephrotic syndrome. Can decrease the permeability of the renal blood vessels to reduce leakage of blood proteins. If patients respond to steroids, have a remission after treatment period. A typical sign of remission of nephrotic syndrome is the relief of protein in the urine.
However, if patients do not respond to steroids, which can cause renal function to decrease rapidly. Therefore, it is important for patients with nephrotic syndrome resistant to steroids to seek alternative treatment.
The treatment for steroid-resistant nephrotic syndrome with protein in the urine
Immunotherapy is an alternative treatment for steroid-resistant nephrotic syndrome. It works in the following ways to treat the disease.
- Remove the inflammatory response in the kidneys.
Immunotherapy can suppress the inflammatory response in kidney. When the immunological damage is inhibited, deteriorating renal function stops.
- Correct the immune dysfunction and rebuild the normal immune system
Abnormal immune system is the underlying cause of the syndrome. nephrotic immunotherapy can correct immune dysfunction and help the body rebuild the normal immune system. If so, the immune system becomes protect the body instead of attacking the kidney tissues.
- Restore the glomerular alteration
Immunotherapy can activate the self-healing and self-healing of glomerular. Once restored impaired glomeruli, renal function improved significantly.
If patients with nephrotic syndrome resistant to steroids have a good response to immunotherapy, which will have a marked improvement. The protein in the urine, swelling, edema and other clinical symptoms be controlled. The creatinine and BUN levels will drop considerably.
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