Purpura Nephritis (or HSP Nephritis, Purpura Nephritis) is an autoimmune disease. Immune complexes deposit on kidneys and launch a series of damages to joint, skin, interstitial tract, etc. Immunotherapy can be used to rectify dysfunction of immune system so as to treat Henoch-Sch?nlein Purpura Nephritis from the root cause.
Allergic purpura nephritis formation process
In healthy case, the immune system can protect the body from the invasion of the pathological substances. Therefore, our body can keep healthy and normal. However, in some cases, the immune system is disordered and it can not function well. When the pathological substances invade into body, the activated antibodies can not eliminate them. The antigens counter and bind to antibodies form immune complexes. These immune complexes flow into kidneys and then deposit in mesangial cells. The body will lead to an inflammatory response to remove the immune complexes from body leading damage to renal cells and tissues. As a result, Purpura Nephritis occurs. In clinic, the patients will present a series of symptoms like proteinuria, hematuria and so on.
Henoch-Schonlein Purpura Nephritis treatment
1. Traditional treatments
The traditional treatments of Henoch-Schonlein Purpura Nephritis treatment mainly include immunosuppressive therapy and hormonetherapy. These two therapies only focus on the symptoms of the disease. Therefore, they can not treat the disease fundamentally or stop the renal function decline. Moreover, once they stop or reduce the dosages of hormones, the disease is susceptible to relapse.
2. The latest therapy-immunotherapy
Immunotherapy is a breakthrough in filed of Kidney Disease treatment. It aims to eliminating symptoms of Henoch-Schonlein Purpura Nephritis from its underlying causes. On one hand, immunotherapy can suppress the abnormal immune response, block the formation of immune complexes as wells as clear up the immune complexes deposited in blood and glomeruli. In this way, the damage to kidneys is inhibited effectively.
On the other hand, immunotherapy can repair the impaired renal tissues and cells due to the inflammation. Moreover, it can rebuild Henoch-Schonlein Purpura Nephritis patients’ immunity system. Therefore, it makes them get rid of the reoccurrence of the disease again effectively.
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