Hypertensive nephropathy can cause great harm, all the body organs and blood vessels. Long-term high blood pressure causes blood vessels to become stiff, leading to vascular fragility. The kidney is the main organ composed of vessels. When hypertension is not well controlled their blood pressure or blood pressure for a long time greatly different, it can lead to kidney blood vessels become more and more hard, fragile, it can easily damage the kidneys and lead to broken blood vessels. As a result, proteinuria can occur, due to decreased glomerular filtration rate and other symptoms.
Hypertensive nephropathy during treatment should pay attention to four major aspects:
1) Expand various renal arterioles. Glomerulus capillaries stand in ischemia and anoxia due to the Hypertensive irritation. The aim to expand arterioles is to improve the blood supply for various systems in renal blood circulation, to alleviate the ischemia and anoxia status of renal inherent cells, which supplies a good environment for endothelial cells’ recovery.
2) Anti–inflammation: reduce the infiltration from inflammatory cells, avoid inflammatory factors’ damage to endothelial cells.
3) Anti-coagulation: reduce the microthrombus development in glomerulus capilleries, make a foundation for endothelial cells’ recovery.
4) Degradation, the augmentation of inflammatory cells in glomerulus capillary will incur excessive secretion of extracellular matrix
For the medical applications, the scientific ways should be the combination or comprehensive use between Chinese and western medicines. Do not use Chinese medicine or western medicine lonely, because there are some restrictions on the curative effect for a single method.
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