2013年10月1日星期二

Complications associated with nephrotic syndrome awareness

Kidneys are important organs in body. They can filter the metabolic wastes and extra water out of body and preserve what the body need in blood. However, in Nephrotic Syndrom, the kidneys leak protein, which normally stay in blood into urine. For the protein in urine, the patients will have a series of symptoms.
Complications of nephrotic syndrome are mainly the following aspects.
1. Infection. Because a large number of immune globulin in urine leak out. Will reduce the amount of plasma proteins, affect the formation of antibodies. Corticosteroids and cytotoxic drugs, will cause the entire body's immune system decline.
2. Coronary artery disease. Nephrotic syndrome may always have hyperlipidemia, and hypercoagulability. Therefore, patients with this disease more likely to get coronary artery disease. It is said that the incidence of myocardial infarction eight times higher than the average person.
3. Thrombosis. Easy to get blood clots in patients with nephrotic syndrome, especially membranous nephropathy. The incidence of this disease is 25-40%. Some causes thrombosis, such as edema, hyperlipidemia, Venostasis. More importantly, the viscosity increased blood concentration.
nephrotic syndrome and secondary nephrotic syndrome. Nephrotic syndrome is due to glomerular disease. In other words, the main pathological changes in the kidney. Secondary nephrotic syndrome caused by systemic diseases such as cancer, systemic lupus erythematosus, amyloidosis, and so on. So, after being diagnosed with nephrotic syndrome, they first have to find a specific reason for the disease, resulting in relative treatment time.

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