For Uremia, children patients and those adult patients who develop Uremia
from urinary system disease when it is procrastinated from childhood to adult,
take a significant proportion. It is because children have a comparative low
resistance which can easily cause repeated infection. Besides, when children
suffer infection, if it is not properly treated, the repeated infection can lead
to damage to kidney or even Uremia. Then, what factors causes children
uremia?
The factors which causes a high incidence of children Uremia are as
follows:
One, the main factor is Chronic Nephritis. The condition of renal ischemia
and anoxia damages glomerular capillary endothelial cells, which actives the
infiltration of inflammatory cells, promotes glomerular pathological changes of
fibrosis. With the condition, mesangial cell produces masses of extracellular
matrixes by phenotype transformation, which replaces and damages renal intrinsic
cell. Besides, the masses generation of extracellular matrixes is not easily
degraded. Consequently, the quantities of renal intrinsic cell are reduced and
scar tissues are formed . As a result the kidneys gradually lose its function of
filtration and excretion, which leads to renal failure.
Second, urinary tract infection is a main factor leading to children
interstitial nephritis, which can be divided into acute urinary infection and
chronic urinary infection. The course less than 6 months is acute urinary
infection and the course more than 6 months is chronic urinary infection. The
prognosis of acute urinary infection is good, which usually doesn't leave
sequela and won't cause renal damage. However, if it is not properly treated and
condition is delayed, acute urinary infection can finally develop into repeated
chronic urinary infection, which damages renal pelvis and interstitial, actives
the formation of renal scar and even causes Uremia.
Three, other factors such as polycystic kidney, Lupus Nephritis,hereditary
nephritis, etc can cause Uremia.
To effectively treat Children Nephritis and prevent from Uremia, patients
should take positive proper treatment. Shijiazhuang Kidney Disease Hospital
takes Immunotherapy and Micro-Chinese Medicine to treat Children Nephritis.