2016年2月9日星期二

What Causes Children Uremia?

For Uremia, children patients and those adult patients who develop Uremia from urinary system disease when it is procrastinated from childhood to adult, take a significant proportion. It is because children have a comparative low resistance which can easily cause repeated infection. Besides, when children suffer infection, if it is not properly treated, the repeated infection can lead to damage to kidney or even Uremia. Then, what factors causes children uremia?

The factors which causes a high incidence of children Uremia are as follows:

One, the main factor is Chronic Nephritis. The condition of renal ischemia and anoxia damages glomerular capillary endothelial cells, which actives the infiltration of inflammatory cells, promotes glomerular pathological changes of fibrosis. With the condition, mesangial cell produces masses of extracellular matrixes by phenotype transformation, which replaces and damages renal intrinsic cell. Besides, the masses generation of extracellular matrixes is not easily degraded. Consequently, the quantities of renal intrinsic cell are reduced and scar tissues are formed . As a result the kidneys gradually lose its function of filtration and excretion, which leads to renal failure.

Second, urinary tract infection is a main factor leading to children interstitial nephritis, which can be divided into acute urinary infection and chronic urinary infection. The course less than 6 months is acute urinary infection and the course more than 6 months is chronic urinary infection. The prognosis of acute urinary infection is good, which usually doesn't leave sequela and won't cause renal damage. However, if it is not properly treated and condition is delayed, acute urinary infection can finally develop into repeated chronic urinary infection, which damages renal pelvis and interstitial, actives the formation of renal scar and even causes Uremia.

Three, other factors such as polycystic kidney, Lupus Nephritis,hereditary nephritis, etc can cause Uremia.


To effectively treat Children Nephritis and prevent from Uremia, patients should take positive proper treatment. Shijiazhuang Kidney Disease Hospital takes Immunotherapy and Micro-Chinese Medicine to treat Children Nephritis.

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