2016年2月2日星期二

The complications of diabetic nephropathy

Diabetic Nephropathy is a serious complex of Diabetes, which may easily develop into Uremia or Renal Failure if not well controlled. It is very important to know the symptoms of Diabetic Nephropathy, which can help patients to seek for treatment timely and won't delay the condition for treatment. Then, what are the symptoms of Diabetic Nephropathy?

1. Edema: patients at the early stage of Diabetic Nephropathy usually have no symptom of edema. A few patients can have slight edema before the decline of plasma protein. When 24-hour protein in urine is more than 3 grams, obvious edema can occur. Besides, obvious edema is only common for patients with rapid progress of Diabetic Nephropathy.

2.Anemia: patients with obvious azotemia can be accompanied with slight or moderate anemia, which can not be corrected with chalybeate. It is caused by defect in erythropoiesis, which is related with long-term restriction of protein intake and azotemia.

3. Hypertension: hypertension is a common symptom of Diabetic Nephropathy. Hypertension can promote the progress of Diabetic Nephropathy or even make it get worse.


4.Proteinuria: MALB can occur when glomerular filtration pressure increases or charge changes on filtration membrane, which is selectivity proteinuria without the increase of globulin and it can persist several years. With the increased enlarging filtration pore of glomerular basement membrane, macromolecular substances can gothrough it, representing nonselective clinical proteinuria. With the condition not well controlled it can lead to serious proteinuria and if the protein in urine is more than 3 grams each day, it may be a sign of bad prognosis. The condition of proteinuria can represent progressive development.

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