Before diagnoses as Nephrotic Syndrome, many children are usually found some infections, such as cold or other inflammations. This confuses their parents that why a cold or an inflammation leads to Nephrotic Syndrome. To explain this clearly, let us see our immune system first.
What are the functions of immune system?
Our immune system is like a precision force which protects our health for 24
hours without stop every day. It is a great masterpiece and can deploy
uncountable and different functions of armies to take complex tasks every
second. It can not only protect us from the harm of foreign invaders, but also
can prevent canceration caused by changes of cells in our body. If there are no
protection of our immune system, even a dust can give us death.
How does immune system work?
When pathogenic micro-organisms, such as bacterial and virus, enter our body,
macrophages in our immune system attack firstly and take those intruders into
their belly and then divide them into pieces of fragment. They present those
fragment on their surface to indicate they have swallowed the invasion bacterial
and let T-cell know. When T-cells meet with macrophages bringing fragments, they
react immediately just like the lock meets the key. Then, macrophages produce a
substance whose mainly function is to activate the T-cell. No sooner the wake of
T-cells than it gives the whole immune system alarm that there are some
intruders. After that, immune system sends destruction T lymphocytes which can
search those infected human cells and destroy them like killers to prevent their
Why cold lead to Nephrotic Syndrome for child?
Cold is belongs to infection and it also cased by some bacterial or virus and
when the body get cold, our immune system sends force to defeat those the
bacterial or virus. However, children have a low immune system, so the immune
cells contain the bacterial or virus temporary forming immune complexes instead
of killing them. Those immune complexes follow blood circulation and deposit on
glomerular basement membrane when the blood flows through the kidneys. This
deposition damages the kidneys and leads the appearance of proteinuria,
eventually leads the occurrence of Nephrotic Syndrome.
What should we do to remedy from Nephrotic Syndrome?
It is obvious that the causes of Nephrotic Syndrome is the damaged glomeruli,
hence, if the damaged glomeruli are repaired, Nephrotic Syndrome disappears