2015年12月21日星期一

Treating Nephrotic Syndrome with Immunotherapy

Nephrotic Syndrome is not an isolated disease, but a group of disease with syndrome caused by various kinds of Kidney Diseases. It is characterized with a large of proteinuria, serious edema, albuminemia and hyperlipemia.

In the conventional therapies, the patients mainly use glucocorticoid and antibiotics to treat Nephrotic Syndrome. No doubt that the hormone therapy has played an important role in treating the disease. The patients’ symptoms can alleviate and even disappear after using it. Therefore, the patients just think that the disease recovers. However, a mild infection such as colds may trigger the disease again and even aggravate the original disease. Facing the troublesome relapses, the patients with Nephrotic Syndrome begin to find a better therapy instead of hormone.

For the patients with Nephrotic Syndrome, proteinuria is the primary cause of other symptoms. Therefore, treating proteinuria is the key in treating Nephrotic Syndrome. In the conventional therapies, as the treatments simply treat the proteinuria, but not its fundamental causes. That is the fundamental cause of relapse of the disease.

In the normal cases, when blood flow through kidneys, the glomeruli can filtrate the harmful wastes out of body and preserve the useful substance in body. However, for the patients with Nephrotic Syndrome, with the decline in the renal function, the glomerular basilar membrane loses the normal filtration and barrier functions. As a result, the protein that body need leaks into urine. Therefore, in order to treat proteinuria, the patients should repair the damaged glomerular basilar membrane. Immunotherapy plays its important role on this point.


Immunotherapys are a group of undifferentiated original cells with differentiation and regeneration abilities. They can regenerate into cells that have the same characteristics with the original cells or differentiate into tissues and cells with specialized functions. In treating Nephrotic Syndrome, Immunotherapy can differentiate into new cells to replace the damaged renal intrinsic cells to play their role. As a result, the glomerular basilar membrane will recover its normal function. In this way, the proteinuria can be treated from its root cause.

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