Glomerular Filtration Rate (GFR) refers to a test which can detect how much
blood is fitered through the glomeruli within a unit time and how much renal
function you have.
The normal range of Glomerular Filtration Rate (GFR)
In general, the normal range of GFR is: male-(125±15) ml/min, female-10%
lower than that of male. The normal range is not fixed (GFR) with the change of
calculating computer, methods or food you take etc.
The clinical meaning of Glomerular Filtration Rate (GFR)
The above mentioned shows that Glomerular Filtration Rate (GFR) can indicate
that how much renal function you have, so it can be used to estimate the damages
of functional nephrons and to help your doctors to make corresponding
treatments.
Changes of Glomerular Filtration Rate levels have clinical meaning as
follows:
■ An elevated level of Glomerular Filtration Rate may indicate:
1) The early stage of diabetic glomerular sclerosis. At that time, the growth
hormone secretion increases, which enlarges the glomeruli, thus the level of GFR
elevates.
2) Some mild Nephrotic Syndrome. The decrease of glomerular capillary colloid
osmotic pressure increases Glomerular Filtration Rate (GFR).
3) Glomerular Filtration Rate (GFR) level also increases in the pregnant
women, which can spontaneously recover after childbirth.
■ A decreased level of Glomerular Filtration Rate may indicate:
1) The appearance of all kinds of primary or secondary disease which can
damage glomerular filtration function.
2) Age also can decrease the level of GFR. After 40 years old, Glomerular
Filtration Rate (GFR) reduces 0.4 - 1.2 ml/min per year.
GFR, as an indicator of your renal function, can reflect the health of
kidneys. Once you detect abnormalities of GFR level, you should consult your
doctor as early as possible or talk with our online experts.