IgA Glomerulonephritis, also known as Berger's disease, IgA Nephritis, refers to a medical condition that causes IgA protein to accumulate in the kidneys. Individuals between the ages of 20 and 40, men individuals with a family history of IgA Glomerulonephritis are more likely to develop this disease. With the developing of the illness condition, many severe complications will appear.
● High blood pressure (hypertension)
High blood pressure is not a desirable complication of IgA
Glomerulonephritis. Damage to the kidneys and the resulting buildup of wastes in
the blood stream can raise the blood pressure. What's worse, hypertension will
in turn aggravate the patients' situation.
● Nephrotic Syndrome
This is a group of signs and symptoms that may accompany IgA
Glomerulonephritis and other conditions that affect the filtering ability of the
Nephrotic syndrome is characterized by high urine protein levels,
resulting in low protein levels in the blood; high blood cholesterol; and
swelling from fluid retention (edema) of the eyelids, feet and abdomen.
● Acute Renal Failure
In IgA Nephropathy, the filtration function of nephrons is damaged, so waste
products will accumulate rapidly. In this case, you have to resort to dialysis
to remove excessive fluid and waste from the blood.
● Chronic Renal Failure
This is an extremely severe complication, and the renal function is impaired
over time. As a result, kidneys gradually lose function. If the remaining kidney
function is less than 10% of normal capacity, you are diagnosed as end-stage
renal disease, which usually requires dialysis or a kidney transplant to sustain
To prevent the appearance of the above serious complications, patients with
IgA Glomerulonephritis should receive scientific treatment in specialized kidney
disease hospital. With the development of medical technology, a systemic
treatment for IgA Nephropathy has been formed, called immunotherapy. It can
block further damages, repair renal intrinsic cells, and has achieved
significant curative effect in clinical.