2015年9月29日星期二

Complications of IgA Glomerulonephritis

IgA Glomerulonephritis, also known as Berger's disease, IgA Nephritis, refers to a medical condition that causes IgA protein to accumulate in the kidneys. Individuals between the ages of 20 and 40, men individuals with a family history of IgA Glomerulonephritis are more likely to develop this disease. With the developing of the illness condition, many severe complications will appear.

● High blood pressure (hypertension)

High blood pressure is not a desirable complication of IgA Glomerulonephritis. Damage to the kidneys and the resulting buildup of wastes in the blood stream can raise the blood pressure. What's worse, hypertension will in turn aggravate the patients' situation.

● Nephrotic Syndrome

This is a group of signs and symptoms that may accompany IgA Glomerulonephritis and other conditions that affect the filtering ability of the glomeruli.
Nephrotic syndrome is characterized by high urine protein levels, resulting in low protein levels in the blood; high blood cholesterol; and swelling from fluid retention (edema) of the eyelids, feet and abdomen.

● Acute Renal Failure

In IgA Nephropathy, the filtration function of nephrons is damaged, so waste products will accumulate rapidly. In this case, you have to resort to dialysis to remove excessive fluid and waste from the blood.

● Chronic Renal Failure

This is an extremely severe complication, and the renal function is impaired over time. As a result, kidneys gradually lose function. If the remaining kidney function is less than 10% of normal capacity, you are diagnosed as end-stage renal disease, which usually requires dialysis or a kidney transplant to sustain life.


To prevent the appearance of the above serious complications, patients with IgA Glomerulonephritis should receive scientific treatment in specialized kidney disease hospital. With the development of medical technology, a systemic treatment for IgA Nephropathy has been formed, called immunotherapy. It can block further damages, repair renal intrinsic cells, and has achieved significant curative effect in clinical.

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