Nephrotic Syndrome is a kidney disorder. It commonly happens in 2~3 year old
children but all ages can be affected. This disease causes large amounts of
protein to show in the urine, which makes the protein level in the blood low.
Then waster will leak into the tissues, causing swelling of the body tissue.
Parents always wonder that how childhood Nephrotic Syndrome occurs. The
following text gives a clear explanation.
According to the newest study, childhood Nephrotic Syndrome usually occurs as
a result of the imbalance, from time to time, of the body's immune system. This
imbalance causes deposits of immune complexes in the filters of the kidneys.
These filters begin to allow proteins to leak into the urine.
Inside our body, there is an amazing protection mechanism called the immune
system. It can defend us against millions of bacteria, microbes, viruses, toxins
and parasites that would love to invade our body. Generally, when a virus or
bacteria invades our body, our immune system will produce certain antibodies to
bind to specific antigens, disable the chemical action of the toxin, and then
remove the invaders, thus protecting the body from these viral and bacterial
infections.
The immune system of your child is not strong enough to fight off these
antigens. Due to immune dysfunction, or abnormal immune system, those antigens
can enter into the body easily. Antibodies fail to remove these invaders but
combine with them, forming immune complexes. The immune complex will circulate
in the blood, and then deposits in the kidneys.
In order to eliminate the immune complexes, immune reaction will occur within
the child's body. However, they are difficult to be removed, and the immune
response become more and more intense, causing damages to the tiny filtering
units of the kidneys, called glomeruli. Over time, childhood Nephrotic Syndrome
will appear.