The Diabetic Nephropathy always happens after ten years since people got Diabetes. Patients may ignore this disease. So it is important to know the symptoms of Diabetic Nephropathy, which can help patients recognize the disease and then take a timely treatment. What kind of symptoms does Diabetic Nephropathy have?
In the early stage, there is always no symptom and the blood pressure is in
normal level or a little higher. When the discharge rate of microalbuminuria is
more than 200mcg/min by using radioimmunoassay method, this is called occult
kidney disease or early-stage kidney disease. If the hypertension and
hyperglycemia can be controlled, the illness condition can get well. But without
a good control, the disease may develop to clinical Diabetic Nephropathy. At
this time, the symptoms of Diabetic Nephropathy can have the following
At the beginning, the increase of glomerular filtration pressure and the
charge changing of filtration membrane will lead to the urine only appear
microalbuminurias. This kind of urine belongs to selective proteinuria and there
is no increase of globulin. This state will last many years. With the increase
of filtration hole of glomerular basement membrane, the macromolecular
substances will cross and cause nonselective clinical proteinuria. With the
continuous development of pathological change, the urine protein will becomes
persistent severe proteinuria. If the proteinuria is more than 3g/d, it is the
symptoms of bad prognosis. The severity of proteinuria of Diabetic Nephropathy
patients always develops continuously until the occurrence of Nephrotic
Diabetes patient with obvious azotemia may have mild to moderate anemia.
There is no effect by using chalybeate treatment. This kind of anemia is caused
by the production obstacle of erythrocyte and it may be associated with the
long-time restriction of protein diet and the azotemia.
3. Hypertension. This symptom is commonly seen in Diabetic Nephropathy
patients. The severe kidney disease may combine with Hypertension, and
Hypertension may also accelerate the process and deterioration of Diabetic
Nephropathy. So it is very important to effectively control high blood
4. Edema. The early-stage of Diabetic Nephropathy patients may don’t have
edema generally. A few parts of patients may have slight edema before the index
of plasma protein decreasing. The edema will decrease when 24-hour urinary
protein is more than 3g. The obvious edema can be seen from the patients with a
quick development of Diabetic Nephropathy.
5. Renal Insufficiency. The Diabetic Nephropathy is a kind of persist
disease. The Azotemia and Uremia is the final stage of this kidney disease.
6. Other symptoms. The diabetic retinopathy is not the symptom of kidney
disease, but it is always accompanying to Diabetic Nephropathy. Some people even
think that without diabetic retinopathy, the Diabetic Nephropathy won’t
The symptoms of Diabetic Nephropathy can be concluded the above aspects.
Diabetic Nephropathy patients should take test regularly. If patients appear the
above one or more symptoms, they should take a treatment timely. Good wishes to
you and your family.