Gout is called ‘hyperur icemia', which is a kind of arthritis. Gout refers to the metabolism of purine in a mess, and then leads to increase the combination of Uric Acid or reduce the discharge, patients present hyperur icemia. When the density of Uric Acid is too high, more and more sodium salt which is made of Uric Acid are deposited in the joint, cartilage, and kidneys, then gives rise to the inflammatory reaction of tissues, that is Gout.
High density of Uric Acid in the human blood leads to the crystallization in
soft tissues, which gives rise to the overreaction of immune system of human
Normally, the most common site is thumb joint, ankle joint, knee-joint
Patients wake up in the middle night because of the severe pain. In the
early stage of Gout, more and more patients have pain in the lower limbs.
Gout can give rise to the kidney damage. According to figures, 20%-25%
patients have uric acid nephropathy. After autopsy proved, almost 100% Gout
patients present the kidney damage.
Clinically, 20% of patients present kidney damage, especially for the renal
tubules and glomeruli, and less people present Uremia. In the early stage,
patients present backpain in one side or two sides of kidneys, light edema and
high blood pressure, acid urine, protein in urine, the concentrating ability of
renal tubules decrease. What’s more, patients present enuresis, more urine. This
disease will develop into Uremia after 5-10 years, and 17-25% patients die of
20%-50% patients with primary Gout present kidney stones, and 85 % of which
belong to Uric acid stone. When the kidney stone become more and more big,
patients present renal colic, hematuresis. In addition, gout patients always
accompany with high blood pressure,obesity, arteriosclerosis etc.
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