Symptoms of Henoch-Schonlein Purpura Nephritis
Henoch-Schonlein Purpura Nephritis is characterized as the damage of kidney
caused by Anaphylactoid Purpura, causes of which can be allergic reactions，such
as the infection of bacteria, viruses, parasites and so on. Besides, different
kinds of stimulation, such as drugs, food, plant pollen, insect bite and cold,
will lead to Henoch-Schonlein Purpura Nephritis as well. Common symptoms of
Henoch-Schonlein Purpura Nephritis can be represented by symmetry purpura
existing in lower limbs, stomachache, hematochezia, painful swelling of joints,
hematuresis and proteinuria. Then, what are symptoms of Henoch-Schonlein Purpura
Nephritis in details?
Main symptoms of Henoch-Schonlein Purpura Nephritis:
Symptoms of digestive system:
The most common symptom of Henoch-Schonlein Purpura Nephritis is
gastrointestinal symptoms. Nearly all of patients are accompanied with
inappetence, abdominal distension, nausea, sickness, sour regurgitation,
belching and so on. Based on clinical researches, main symptoms of
gastrointestinal tract ulcer are slight sickness and melena, the incidence of
which has reached up to 18%~24%.
Symptoms of hematologic system: Uremia patients, carrying with renal anemia,
are accompanied with the tendency of mucocutaneous haemorrhage, symptoms of whom
are subcutaneous ecchymoses, gum haemorrhage, epistaxis and so on.
Symptoms of cardiovascular system: the incidence of patients who are
accompanied with Uremia and Renal Hypertension, takes up 80%~90%, symptoms among
them are headache and dizziness. Besides, serious patients are accompanied with
sickness, hyperspasmia. What’s more, the incidence of Uremic Pericarditis has
increased to 60%~100%, 30%~40% of which belong to pericardial effusion caused by
Uremic Pericarditis. In addition, precordium discomfort, Chest distress and
chest pain are also main symptoms. However, pathological change of
cardiovascular system is the main reason leading to death of patients Uremia,
which takes up 64.3%.
Neuropsychiatric symptoms: the incidence of patients with neuropsychiatric
symptoms has reached up to 13%~18%, main symptoms of which are disturbance of
consciousness, damage of cranial nerve, myospasm and epilepsia.
Respiratory system symptoms: the incidence of lung infection is 50%, most
common symptoms of which are tracheitis, bronchial pneumonia, and purulent
bronchitis. Low immunologic function is another common symptom.
On the other hand, the typical feature of renal damage for patients with
Henoch-Schonlein Purpura Nephritis is hematuria, which may be accompanied with
proteinuria, edema and hypertension in different levels. A small number of
patients present Nephrotic Syndrome or Acute Nephritic Syndrome with renal
function decreasing.