IgA Nephritis is named for the deposits of IgA immune complex in the kidney filters, or glomeruli. It affects millions of people all over the world. Except for the cases of rapid progression, most patients with the disease will lose kidney function slowly, ultimately progress to Renal Failure. Those who have end-stage renal disease (ESRD) may consider to undergo a kidney transplant. Will IgA Nephritis relapse after a transplant?
Recurrence of IgA Nephritis after a kidney transplant is fairly common, and
on average, around 2.5 years after the transplant. But it can happen at any
If a kidney biopsy is done for all transplant patients with this disease,
approximately 60 percent of them may have evidence of this illness in the sample
of biopsy. However, not each of patient would have signs or other abnormal test
results. About 20 to 40 percent of patients may have abnormal protein or blood
in the urine as a result of the relapse of the disorder.
Generally, after about 5 years of the transplant, patients have increased
rate of kidney loss, and around 40 percent of patients who experienced recurrent
IgA Nephritis will finally lose their kidney. This would happen after 10 years
Therefore, patients should be aware that a renal transplantation is not a
cure for the disease, merely a replacement organ. It is wise for individuals
with this disease to find a better cure for IgA Nephritis.
IgA is a kind of autoimmune disease. This is a disease in which the person's
own immune system attacks their own body due to immune dysfunction. As a result,
large amount of IgA immune complexes will deposit in the glomeruli, causing the
inappropriate immune response.
At present, the latest treatment for IgA Nephritis is Immunotherapy in
Shijiazhuang Kidney Disease Hospital. This therapy is developed based on 26
years' research and clinical practice in treating IgA kidney disease. Refer to
"The Latest Treatment for IgA Nephropathy: Immunotherapy" for better