FSGS is an autoimmune disease, and the main cause is glomerular epithelia has
been damaged. Over time, the damage to the kidneys may lead to kidney failure,
or end-stage renal disease (ESRD). About half of FSGS patients who do not
respond to steroids go into ESRD each year, requiring kidney transplant.
However, within hours to weeks after a transplant, the disease returns in
approximately 30%~40% of patients. So, it is wise for patients to find a better
thorough treatment.
What causes the relapse of FSGS after a kidney transplant?
FSGS is often caused due to low immunity. When the immunity is low, immune
disorder can be caused easily, leading to allergic immune response. In this
condition, too many complexes such as IgM, C3 will deposit in the kidney,
causing poor supply of blood and oxygen of the kidney. As a result, the
epithelial cells are damaged. The damaged epithelia will bring inflammatory
factor which will aggravate the damaged kidney.
A kidney transplant can just replace the damaged kidney, and cannot improve
the disordered immune system, so the disease will recur again.
Therefore, if we want to treat the disease effectively, we must block the
allergic immune response, repair the damaged renal epithelial cells and regulate
the disordered immune system.
As one of the largest kidney disease specialized hospital throughout the
world, we're making great strides toward advanced therapies for kidney diseases.
We have found the most-successful way to treat FSGS. That is the latest
Immunotherapy.
This is a systemic treatment which includes six steps: an accurate diagnosis,
immune blocking, immune tolerance, immune regulation, immune protection, and
immune clearance. Refer to "Alternative Treatments for FSGS Kidney Disease".
Steps are selected to treat FSGS based on personalized illness condition.
With this new Immunotherapy, the disease can be treated from the root without
kidney transplant.