2015年6月26日星期五

Do Exercise and Weight Loss Affect Serum Creatinine in a PKD Patient

When the kidneys are functioning normally, the amount of creatinine in the serum should keep even. If the they are not working properly, the level of serum creatinine will becomes elevated. This level is usually used to determine how well one's kidneys are functioning. Normal levels of blood creatinine are about 0.6~1.2 mg/dL in adult male and 0.5~1.1 mg/dL in adult female. For individuals with PKD, will exercise and weight loss affect their levels of creatinine in the blood?

Exercise and serum creatinine

Generally, moderate exercise will not affect the creatinine levels. However, with continuous exercise and build of muscle mass, the levels may increase slightly but not to abnormal degrees.

Weight loss and serum creatinine

In fact, obesity is associated with hyper-perfusion of the kidneys or increased Glomerular Filtration Rate (GFR). After lose weight, there are decreased renal plasma flow, GFR, and albumin excretion rate in affected people. With improvement in kidney function, serum creatinine level will reduce in a certain degree.

Therefore, we can conclude that both exercise and weight loss can affect your level of creatinine in blood. Then, what's the best way to reduce high creatinine levels in PKD?

Firstly, we should make the underlying causes clear. The fundamental cause of your problem is damaged kidney function, which is the result of the suppression of enlarged renal cysts. In order to bring the serum creatinine back to normal range, we must find a good way to restrain the growth of cysts and make them become smaller and smaller. In this way, we can avoid further deterioration of kidney function.


In addition, restoring the damaged kidneys is also necessary. With normally functioning kidneys, high serum creatinine in PKD will be eliminated successfully.

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