When the kidneys are functioning normally, the amount of creatinine in the serum should keep even. If the they are not working properly, the level of serum creatinine will becomes elevated. This level is usually used to determine how well one's kidneys are functioning. Normal levels of blood creatinine are about 0.6~1.2 mg/dL in adult male and 0.5~1.1 mg/dL in adult female. For individuals with PKD, will exercise and weight loss affect their levels of creatinine in the blood?
Exercise and serum creatinine
Generally, moderate exercise will not affect the creatinine levels. However,
with continuous exercise and build of muscle mass, the levels may increase
slightly but not to abnormal degrees.
Weight loss and serum creatinine
In fact, obesity is associated with hyper-perfusion of the kidneys or
increased Glomerular Filtration Rate (GFR). After lose weight, there are
decreased renal plasma flow, GFR, and albumin excretion rate in affected people.
With improvement in kidney function, serum creatinine level will reduce in a
Therefore, we can conclude that both exercise and weight loss can affect your
level of creatinine in blood. Then, what's the best way to reduce high
creatinine levels in PKD?
Firstly, we should make the underlying causes clear. The fundamental cause of
your problem is damaged kidney function, which is the result of the suppression
of enlarged renal cysts. In order to bring the serum creatinine back to normal
range, we must find a good way to restrain the growth of cysts and make them
become smaller and smaller. In this way, we can avoid further deterioration of
In addition, restoring the damaged kidneys is also necessary. With normally
functioning kidneys, high serum creatinine in PKD will be eliminated