Normally, a person loses less than 150mg of protein in the urine in a 24-hour
period. Therefore, the detection of abnormal quantities of protein in urine may
be considered as early sign of significant kidney disease. In Nephrotic Syndrome, proteinuria is the primary indicator of the disease.
Underlying mechanisms
Healthy kidneys are responsible for cleansing our blood. The kidney is made
up of millions of small filtering units-glomeruli. In these filtering units,
waste products and excess fluid pass through the filter and are removed into the
urine, whereas the substances that are useful to the body like proteins, blood
cells, etc don't pass the filter and remain in the blood.
NS is an immunological disease caused due to low immunity or abnormal immune
system. Patient's immune system fails to defends the body against what it
perceives to be foreign or dangerous substances. In this condition, immune
complex will be formed after the germs that invaded into the body bind with the
antibodies produced by the immune system.
There are special epitopes in the kidneys that attract the immune complex, so
more and more immune complexes will get deposited in the kidneys, causing damage
to the filters and the glomeruli become leaky. This causes a loss of protein
into urine (proteinuria).
How to reduce protein in urine due to NS?
Once people with NS detect protein in urine, they should take prompt
treatment. If the underlying cause is not eliminated, the kidneys may be damaged
further. Treating proteinuria is one way to maintain a healthy kidney.
Immunotherapy is available in China to cure protein in urine:
▪ New immunosuppressive drugs --restrain the abnormal immune response;
▪ Immune tolerance -- avoid further kidney damage;
▪ Micro-Chinese Medicine Osmotherapy -- promote renal blood circulation,
eliminate the deposits of immune complex in glomeruli, and accelerate the kidney
repair;
▪ Immunotherapy -- restore the kidney function and rebuild the immune
system.