Fatigue is the dominant complaint of most people with IgA Nephropathy, which 
can be overwhelming. At times, it may be accompanied with a sore throat, fever, 
or headache. Typically, the fatigue goes together with incidents of blood and 
protein in the urine. Treatment for this condition often varies with different 
causes.
What causes fatigue in IgA Nephropathy?
In general, there are several reasons that can lead to this condition as 
following:
▪ Anemia, a shortage of oxygen-carrying red blood cells.
People with kidney problems often have anemia because damaged kidneys produce 
less of a hormone called erythropoietin, or EPO. EPO tells the bone marrow to 
make new red blood cells. Without a fresh supply of red blood cells, the body 
has less oxygen. This makes patients more tired and cold, and less able to focus 
and fight disease.
▪ Lifestyle factors, such as alcohol use or abuse, caffeine use, excessive 
physical activity, inactivity, lack of sleep, unhealthy eating habits, etc. 
Besides, certain medications may also cause drowsiness or fatigue, including 
blood pressure medicines, steroids, diuretics and so forth.
▪ Mental healthy problems, such as anxiety, depression, grief, and 
stress.
How to treat fatigue in IgA Nephropathy naturally?
1. Find a standard treatment to repair the damaged kidneys and restore the 
renal function. Nowadays, the newest therapy for this disease is known as 
Immunotherapy. As a holistic treatment, this treatment can eliminate the 
symptoms of IgA kidney disease, prevent the progressing, recover the kidney 
function, and regulate the overall immune system.
2. Quit the unhealthy living habits and develop a healthy lifestyle can help 
relieve the discomfort in a certain degree.
3. Maintain a good mental state and keep a positive attitude toward 
overcoming the illness through receiving vigorous treatment.