2015年8月24日星期一

Treat IgA Nephropathy Effectively with Plasma Exchange

Mr. Wu, Male, 22 years old, was diagnosed with IgA Nephropathy 7 years ago. He came to our hospital on Feb. 5, 2012 for better treatment. After twenty days' treatment, the condition has been improved to large extent. Mr. Wu feels satisfying to his curative effects. He was discharged from our hospital on Feb. 25, 2012. The following gives detailed information.

Tests Before treatment:

1. Bp 140/90mmHg; height 160cm; Weight 46kg. 2. Routine urine test: proteinuria ++, occult blood ++

3. Urine Specific Gravity 1.008; PH 5.5 urine 4. Urine protein 3.59g/24h

5. Blood: Total protein 58.6g/L; Albumin 30.4g/L; ALT 5.1U/L; AST 11.4U/L; hemoglobin 112g/L

6. Creatinine 240umol/l; BUN 7.4mmol/L; UA 589umol/l

Blood: K+ 4.08mmol/L; Na+ 142mmol/L; Cl- 108mmol/L; Ca 2.2 mmol/L; CO2 21.7mmol/L; PO4 1.89mmol/L

Immune diagnosis:

1. Urine Total Protein: 4599mg/l, MAU 3695mg/l, NAIGG G481.5mg/l, urine α-1 microglobulin 48.9mg/l

2. Six check of Blood fat: LDL 3.53mmol/l, lipoprotein a 885mg/l

ECT: left kidney GFR24ml/min, right kidney GFR32ml/min; decreased GFR, moderate damage of renal filtration function.

Treatment:

1. Western medicines were used to control the complications;

2. Plasma Exchange in Feb. 16 and Feb. 22 3. Micro-Chinese Medicine was applied to stop the renal fibrosis.

Curative effects:

1. Bp 100/70mmHg; 2. poteinuria +; 3. Urine Specific Gravity 1.025;

4. Urine protein 1.23g/24h; 5. MAU 1589;

6. Blood: RBC 8.6/ul; K+ 4.308mmol/L; Na+ 13708mmol/L; Cl- 10208mmol/L; PO4 0.9308mmol/L;


Albumin 45.6 g/L; Creatinine 157 BUN 7.64mmol/L; UA 336umol/l.

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