Diabetic Kidney Disease, also known as Diabetic Nephropathy, is a progressive disease characterized by nephrotic syndrome and diffuse glomerulosclerosis. It is due to longstanding diabetes, and is the most common cause of chronic kidney failure and end-stage renal disease (ESRD) in the United States. Diabetic Kidney Disease continues to get gradually worse, and complications as below can be caused.
1. Hyperkalaemia-the failing kidneys fail to excrete potassium. In advanced
chronic kidney disease, uncontrolled hyperkalaemia indicate need for
2. Cardiovascular events-DN is complicated by a triad of inflammation,
endothelial dysfunction and oxidative stress and is associated with marked
cardiovascular morbidity and mortality.
3. Refractory hypertension-with the progressive loss of kidney function, high
blood pressure will become very difficult to control.
4. Anaemia-as the disease progresses, there is an increasing prevalence and
severity of anaemia.
5. Hypoglycaemia-this can be caused due to intensive treatment of
hyperglycaemia because of impaired gluconeogenesis and because insulin and other
oral hypoglycaemics are poorly cleared by the kidney.
6. Chronic renal failure requiring dialysis-patients with macroalbuminuria
often die due to cardiovascular causes before developing into ESRD.
Initially, medicines are often used to treat Diabetic Kidney Disease and
control blood pressure, but patients still have great chance to eventually
develop kidney failure. When that occurs, it is likely you will need dialysis
treatment or a kidney transplant.
In 2012, experts in Shijiahzhuang Kidney Disease Hospital develop an
innovative treatment, called immunotherapy. Through eliminating the root cause
and regulating the overall immune system, you kidney disease can be treated from
the root, so further progression can be stopped. Early treatment may even
reverse Diabetic Nephropathy.