2015年8月29日星期六

Causes of High Blood Pressure in Nephrotic Syndrome

Healthy kidneys play several vital functions, such as filter blood, remove waste products from the body, balances the body's fluids, and releases hormones that regulate blood pressure. A number of diseases and conditions can damage the kidney's filtering apparatus, like diabetes and immune disorders. This damage leads to a condition called Nephrotic Syndrome, which is featured by proteinurina, high cholesterol and triglycerides, and edema. Persons with Nephrotic Syndrome may develop high blood pressure at advanced stage.

What causes high blood pressure in Nephrotic Syndrome?

Kidneys can filter roughly 150~200 quarts of blood every day through tiny structures known as nephrons. There are around one million nephrons in each kidney, and each nephron consists of a glomerulus, the filtering unit of blood vessels. Blood passes through the glomerulus, where various substances are either restrained or removed from the filtrate as necessary. In most cases, filtered sodium and fluid is excreted.

In Nephrotic Syndrome, high blood pressure may occur due to damages to the glomeruli in the kidney's nephrons. When the capillaries of the kidneys are impaired, there will exists a short supply of blood and oxygen in the kidneys.

There is an aotomatic system within our body which can control the blood pressure, called renin-angiotensin-aldosterone system (RAAS). In case of renal ischemia and anoxia, RAAS system can be activated, so the secretion of renin increases, leading to the increase of angiotensin II activity and the striction of arteriolar walls, and then result in high blood pressure.

High blood pressure will in turn causes deterioration of the kidney damages in Nephrotic Syndrome. In repaid deterioration cases, Renal Failure, or even end-stage renal disease can be the result. Therefore, we need to treat high blood pressure in Nephrotic Syndrome as soon as possible.


In China, Micro-Chinese Medicine Osmotherapy is applied to improve the blood circulation, remove the blood stasis, thus reducing high blood pressure consequently. As a Chinese herbal medicine, it has not any side effects, so Micro-Chinese Medicine has been adopted by more and more persons with kidney diseases.

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