Focal Segmental Glomerulosclerosis (FSGS) is difficult to treat. Majority of patients with this disorder progress to ESRD over 5 to 20 years. In some cases, patients with an aggressive form of FSGS proceed to ESRD in 2 to 3 years. Conventional treatments involve steroids or other immunosuppressive drugs to help relieve the symptoms like Urine Protein. But these therapies fail to restore the overall renal function, so it is wise to find better comprehensive solutions.
FSGS is a kind of autoimmune disease mediated by immune cells. The
infiltrating T cells in the glomeruli attack the kidney inherent cells directly
or damage the epithelial cells by releasing vascular permeability factors. To
treat this disease, we have to firstly control the immune reaction and at the
same time remove the immune complex deposited in mesangial region.
For FSGS, the immune complex mainly consists of IgG and C3. This has been
identified with series of immune tests. Only if we remove the immune complex
deposited in the kidneys and recover the kidney function, can the disease be
treated from the root. Otherwise, whenever we stop the steroids, the immune
reaction will start again and the disease will relapse.
The fact is that, currently, there is not yet an effective medicine which can
help us remove these deposits rapidly. Therefore, immune tolerance is developed
to make our body temporarily co-exists with the immune complex so as to stop
further inflammatory reaction. Small dose of immune blockers are given regularly
to avoid the relapse of the disease. Besides, periodical evaluation of immune
reaction in the kidneys can ensure the accuracy of immune blocking.
Immune tolerance is just a interim measure, in the following immune
adjustment step, we will begin to remove the immune complex with Chinese
medicines including oral medicine, Micro-Chinese Medicine Osmotherapy, and
Chinese medicine for nourishing Qi and blood can be used to strengthen
immunity. Moreover, Micro-Chinese Medicine Osmotherapy is another therapy which
can function to promote blood circulation and remove blood stasis. Chinese
medicine is micronized into one thousandths granules. With the action of the
microwave, they can arrive directly at the renal lesions through skin and
channels on the back. More important, this remedy can help us activate the
self-healing ability of the kidneys and provide necessary nutrients at the same
time to speed up the repair of damaged renal cells. Consequently, kidney
function of FSGS will get restored over time.