2012年9月24日星期一

The Prognosis of Nephrotic Syndrome


The prognosis of Nephrotic Syndrome varies and it is largely dependent on the treatment method. Generally speaking, the prognosis of Nephrotic Syndrome will be affected by the following factors.

1. The prognosis of Nephrotic Syndrome is closely related with the diseases that caused it. Nephrotic Syndrome which is caused by tonsillitis or hemolytic streptococci infection has a better prognosis, while the one caused by systemic disorders has a poor prognosis.

2. Clinical manifestations: if patients do not have other symptoms except pure proteinuria and microscopic hematuria, they can have a better prognosis; patients who do not have high blood pressure will get a better prognosis than those with continuous high blood pressure. Patients who have continuous anemia which is not easy to improve have a bad prognosis.
3. Pathologic types: patients with light and focal Nephrotic Syndrome can be cured; however, patients with mesangial and proliferative Neprhotic Syndrome have a bad prognosis; if patients with severe pathological changes such as crescents and glomerulonephritis will have a bad prognosis.

Different types of Nephrotic Syndrome have different prognosis

1. Kidney disease of minimal changes
This type is very common and its complications can be alleviated naturally when this kind of diseases appear. Ninety percents patients with this disease can be effective with treatment of hormone. However, the recurrence of this kind of disease is up to 60%.

2. Mesangial and proliferative glomerulonephritis
Most patients with this type have got infection and received the hormone treatment before developing this disease. Their prognosis is closely related with their severity of pathological changes.

3. Capillary glomerulonephritis in mesangial area
This kind of disease is difficult to treat because hormones and cytotoxic drugs can be effective only on part of children. Adults with this disease develop fast and 10 years later 50% of those patients might develop to Chronic Renal Failure.

4. Membranous Nephropathy
This type of disease always appears in the middle age and old age people with Nephrotic Syndrome. The onset of this disease is slowly and concealing and it can easily lead to thrombus and embolus which will cause the damage of kidney after five years of onset.

5. Focal and Segmental Glomerulonephritis
Part of patients with this disease might develop from minimal pathological changes. Hormone and cytotoxic drugs therapeutic reacts very slowly, but 50% can be alleviated clinically.
The prognosis of Nephrotic Syndrome is greatly affected by various reasons. If patients adopt the adequate therapy, take medicine as prescribed and have a proper diet, your prognosis will be very well.
From the above introduction, we might probably know that Nephrotic Syndrome is a Chronic Kidney Disease which is difficult to treat. However, if the treatment method is right, there is still hope to cure Nephrotic Syndrome.

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