2012年9月15日星期六

Can IgA Nephropathy Patient get married and Have Children?


The clinical manifestations of IgA Nephropathy are the recurrence of gross hematuria and proteinuria. The reason why patients present this phenomenon is that the immune complex deposited in the renal glomerular basement membrane, which cause glomerular ischemia and hypoxia and increasing the permeability of basement membrane barrier, then lead to the leakage of red bloods from the damaged basement membrane. Nowadays, following with the development of society, more and more young people are suffering IgA Nephropathy, so they begin to worry about these questions like "Can IgA Nephropathy patient get married? Can IgA Nephropathy patient get pregnant?" We will explain in the following articles.

"Can IgA Nephropathy patients get married?" The answer is yes, but we should treat the disease seriously. Doctors have suggested that IgA Nephropathy patients should wait after their condition become stable, they can get married and have baby. Women can get pregnant after 2-3 years when the indicators of various urine tests become negative, but in the period of pregnancy, the patient need to do the regular check, follow up the doctors' instructions.

IgA Nephropathy male patients need to pay attention to physical strength, not get tried excessively, and have a degree of sex. If IgA Nephropathy female patients are in an unstable disease condition, it is not easy for them to be pregnant. On the one hand, abortion is bad for fetus, on the other hand, abortion is bad for mother's body, even aggravate the development of illness condition rapidly. So patients should treat these things seriously. If patients pay no heed to this things, the illness condition will relapse even become more and more serious.

IgA Nephropathy female patients have the chance of conception if their illness conditions are stable, but for those patients who have incontrollable high blood pressure, the glomerular filtration rate is lower than 70ml/min, or have lesions of renal artery and renal interstitial when they are puncturing, these things will increase the risk of occurring abnormal renal function.

The risk includes mothers' high blood pressure and aggravating renal function, which lead to abortion, premature birth and intrauterine fetus grow slowly. The evidence of this passage comes from a Japanese study, from 1970—1988, the Japanese scholars have observed 118 IgA Nephropathy female patients with pregnancy for 168 times, they have found that 9 cases of IgA Nephropathy female patients abortion, and most women can delivery normally; but the IgA female patients with high blood pressure and kidney's function are lower than 70ml/min, the fetal mortality is higher several to dozen times than others. So, the study showed that for most patients, pregnancy is not a difficult task, unless the patient who has incontrollable high blood pressure, the glomerular filtration rate is lower than 70ml/min.

But the study has passed for nearly 20 years. In the 20 years, the medicine has more recognization for the IgA Nephropathy, especially after 1999,the research about using hormone and cyclophosphamide to treat IgA Nephropathy has developed by leaps and bounds, also get good clinical result, the Chinese medicine have the protective function for kidney, and more and more IgA Nephropathy patients have optimistic attitude for the clinical result. The IgA female patients have more and more chances to get pregnant.

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