Complications of Nephrotic Syndrome -- How Much Do You Know?

How much do you know about the complications of Nephrotic Syndrome? Nephrotic Syndrome is not an independent disease but a group of symptoms of glomerular disease. Its main symptoms are a large amount of proteinuria, high degree of edema, hyperlipidemia, hypoproteinemia, which is called “Three Highs and One Low”. Nephrotic Syndrome can be divided into Primary and Secondary based on the causes.

Patients with Nephrotic Syndrome are increasing year by year, but few people know about its complications, which is important to patients. We will introduce the complications in detail.

1. Coronary Heart Disease: Hyperlipidemia is one of the symptoms of Nephrotic Syndrome, so patients with Nephrotic Syndrome may get Coronary Heart Disease easily. The incidence of Myocardial Infarction in Nephrotic Syndrome patients is eight times higher than that in normal people. Coronary Heart Disease has become the third factor of Nephrotic Syndrome death.
2. Infection: A large amount of immunoglobulin loses in urine and plasma protein decreases, influencing the formation of antibody. The application of adrenocorticotropic hormone and cytotoxic drugs make systemic resistance of patients decrease, thus infections occur easily, such as skin infections, primary peritonitis, respiratory infections, urinary tract infections and even septicemia.
3. Formation of thrombus: Patients of Nephrotic Syndrome may have thrombus easily. Especially, the occurrence of membranous nephropathy can be 25% to 40%. Causes of thrombus are swelling, less activities, venous stasis and high cholesterol.
4. Acute Renal Failure: When patients vomit, have diarrhea and use antihypertensive drugs and diuretics, renal blood perfusion decreases suddenly and glomerular infiltration rate decreases, causing Acute Renal Failure.
5. Electrolyte and metabolic disorders: Repeatedly use of diuretics or unreasonable salt ban can make patients with Nephrotic Syndrome have secondary hyponatremia. If patients use adrenocorticotropic hormone and large quantities of diuretics, a large number of urination will occur. If patients do not take potassium timely, they may have the symptom of hypokalemia.
What mentioned above is about the complications of Nephrotic Syndrome. If you have any questions about Nephrotic Syndrome, please email to renalhealth@hotmail.com and we will do our best to help you. Wish you have a good day!