2015年7月21日星期二

What Causes Nausea and Vomiting in Renal Failure

Normally, the blood will flow through the kidneys and allow them to excrete wastes and conserve electrolytes (mineral salts). Any condition that significantly interfere with blood flow to the kidney can lead to the loss of kidney function, thus eventually resulting in Renal Failure. Nausea and vomiting are typical symptoms of kidney failure and can greatly affect the quality of life and the appetite of the patient. How does this occur?

Definition

Nausea refers to the feeling of having an urge to vomit, which is often called being sick to your stomach.

Vomiting, or throwing up is forcing the contents of the stomach up through the esophagus and out of the mouth.

The severity of the above two symptoms may vary from patient to patient in different stages. Generally, this phenomenon is more serious in the morning.

Causes

For people with Renal Failure, most of their kidney function has been damaged, so the kidneys cannot function adequately, causing accumulation of wastes and toxins throughout the body. With the severe decline of renal function, the amount of nitrogen in the blood (in the form of urea) will gradually build up, resulting in elevated BUN levels. Meanwhile, urease in the intestinal tract can decompose BUN into ammonia. As the level of BUN increases, large amounts of ammonia will present, thus stimulating the gastrointestinal tract and causing nausea and vomiting.


Why will you suffer from more severe discomforts in the morning? For some Renal Failure patients who suffer from frequent urination at night, there is a large quantity loss of water in the night, which leads to hemoconcerntration, a condition with increased concentration of cells and solid in the blood. As a result, the blood urea nitrogen level will raise in the morning. Series of reactions will lead to your severe nausea and vomiting in the morning.

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