2015年7月8日星期三

How Long does It Take for Toxins to Build up with ESRD

End-stage renal disease (ESRD) is the final and most serious stage of Renal Failure. Generally, patients with this disease may have entire loss of kidney function, or function below 10% of capacity. Toxins and other fluids will build up in the body, resulting in severe symptoms. How long does it take for toxins to build up?

In ESRD, toxins slowly build up in the body. Normally, kidneys can remove these harmful substances from the body via the passage of urine. Most commonly, these toxins measured include urea (BUN) and creatinine. The period of the toxins accumulation depends on the deterioration of kidney function. With a rapid loss of renal function, these substances will accumulate quickly, resulting in some severe symptoms as below:

▪ Weight loss

▪ Muscle cramps

▪ Decreased alertness

▪ Nausea and vomiting

▪ Blood in the vomit or stools

▪ Discolored skin pigmentation

▪ Decreased sensationin the hands, feet, or other areas

▪ Significantly reduced output of urine or no urine output

Is there any treatments for the toxins building up in ESRD?

Usually, patients have to start frequently dialysis to remove toxins from the body. Besides, kidney transplant is the most effective for patients. Both of these treatments are costly and patients also suffer from many severe side effects which can be fatal. So people are always trying to find better treatments.


The good news is that in 2012, immunotherapy is developed in China. So far, it is the most effective treatment for kidney disease. As for ESRD patients, latest immunotherapy can help to stop the deterioration of illness, protect the healthy renal cells and tissues, improve the kidney function through restore the damaged kidneys, and rebuild the immune system. With gradual improvement of renal function, toxins will be excreted from the body effectively, and various symptoms will disappear.

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