2015年7月17日星期五

What Causes Big Puffy Cheeks in Nephrotic Syndrome

Face is the indicator of human health. Anything that goes wrong inside our body is reflected first on face. Big puffy cheeks can usually be found in persons with Nephrotic Syndrome (Nephrosis). What's the reason?

Kidneys are two of the most important organs in our body. Their chief role is to filter waste and excess water our of the body, while restraining useful substances like protein. We call the filtering units glomeruli. Nephrosis is a kidney disorder caused due to a defect in the glomeruli.

When the glomeruli are damaged, the filtering mechanism does not function adequately. Instead of keeping proteins in the blood, the glomeruli filters leak. Therefore, the proteins will be released out of the blood with waste products and waste, and enter the urine.

Large amounts of protein loss from the blood allows the fluid to leak out of the blood into the body's tissues. The fluid retention make the body, especially the face and legs, a puffy and bloated appearance.

Therefore, the cause of your big puffy cheeks is massive loss of protein, so in order to eliminate your discomfort, we need to cure proteinuria firstly by repair the damaged glomerular filtering membrane. This membrane is mainly make of renal intrinsic cells, such as epithelial cells and endothelial cells. So it is necessary to find an effective therapy to repair the damaged intrinsic cells, restore the glomeruli's function, and rebuild the kidney structure. Only in this way, we can get rid of the big puffy cheeks permanently.


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