2015年4月5日星期日

Diagnosis and Immune Tests of IgA Kidney Disease

An early and exact diagnosis of IgA Nephropathy can contribute to better treatment effects. In our hospital, except for regular diagnostic tests of IgA Kidney Disease, we have series of immune tests as below:

1. Hematuria position

▪ Glomerular hematuria: flow urinary sediment non-uniformity red blood cells; urinary red blood cells form deformation (red blood cells>75%); ALB/UTP 0.73±0.11.

▪ Non-Glomerular hematuria: flow urinary sediment uniformity red blood cells; urinary red blood cells form deformation (red blood cells<50%); ALB/UTP 0.41±0.14.

▪ Mixed hematuria: both non-uniformity red blood cells and uniformity red blood cells are detected in the urine.

2. Series of Kidney Damage Tests

It may include: UTP, U-malb, U-TRF, U-IGG, β 2-microglobulin, α1-microglobulin, κ light chain, λ light chain, U- NAG, U-GGT, and Uosm.

Aims: 1) judge whether patient's kidney has been damaged; 2) the injured part: glomerulus or renal tubules; 3) severity of the damage which can instruct the medicine choice; 4) instruct the medicine use in clinic.

3. Uremic toxins tests

Check items include BUN, Creatinine, UA, β 2-microglobulin, CycC, RBP, HCY, PTH.
Aims: 1) make the toxic accumulation in patient's body clear; 2) instruct the choice of immune clearance method.

4. Series of Complement Tests

It can make the activation of completes clear, and it is the index of disease. Check items include C3, C4, CH50, C1q, B factor. The decrease of C3, C4, CH50, C1q indicate the activation of classical pathway, and the decrease of C3 and B factor suggests the activation of side pathway.

If you have been diagnosed with IgA Kidney Disease, we're here to help. You can email to kidney-treatment@hotmail.com or call +86 311 89261580.

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