Refers to inflammation membranous nephropathy glomerular membrane. Proteinuria is an important symptom of membranous nephropathy. Well, then, why proteinuria occurs in membranous nephropathy? What is the right treatment for proteinuria? Is dangerous symptom?
Proteinuria in membranous nephropathy
Clinical diagnosis of membranous nephropathy depends on outcome of renal biopsy and analysis of clinical presentations. A session of renal tissues are removed during renal biopsy, which determine the underlying condition is damaged glomerular basement membrane (GBM). GBM cells stop proteins in urine from leaking. Infections, autoimmune diseases and certain medications may be predisposing to the disease. Under microscope, large numbers of antigen-antibody immune complexes are deposited on glomerular capillary epithelial cells, thickening of glomerular basilar membrane and damage functions glomerular filtration filter. Thus a higher level of protein will be present in urine.
Membranous nephropathy proteinuria treatment
Compared to adults, children suffer with this disease tend to have a better rate of self-referral and better prognosis. The duration and extent of proteinuria are mulled be closely linked with the prognosis of membranous nephropathy. At up to 50 percent of cases, patients develop in terminal renal failure in an average of 15-20 years. The management of proteinuria is one of the important aspects for treating the disease. Controlling blood pressure help reduce glomerular filtration pressure sender and proteinuria. Hormones and immunosuppressive drug treatment will control inflammation in the kidneys as this will help reduce proteinuria. Balance your protein intake also helps control the symptom ---- protein intake should compensate for the loss of protein, but should not be too much to worsen proteinuria.
More importantly, as mentioned above, results in thickening proteinuria and glomerular cells injured. To treat the symptom, more effective treatment may involve reducing the accumulation of immune complexes, correct and improve immune disorder damaged kidneys. In view of this point, immunotherapy treatment is a better option that combines Western medicine and traditional Chinese medicine therapy holism.
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