Polycystic kidney disease (PKD) is a disorder in which clusters of cysts
develop primarily with the kidneys. Cysts are noncancerous round sacs containing
water-like fluid. What are symptoms of Polycystic Kidney Disease?
▲ Pain of renal area is a major symptom. It usually refers to constriction or
dull pain, sharp pain, sometimes abdominal pain or tenderness. The pain may
become serious after doing manual work, long-time work or sitting. The pain may
also result from the internal haemorrhage of kidneys, kidney stones movement or
infection.
▲ Nephromegaly. Due to inconsonant development of bilateral kidneys
condition, their sizes are different. In the late stage of Polycystic Kidney
Disease, the two kidneys can fill the whole enterocoelia. There are many cysts
on the surface of kidneys, which are irregular in outline and solid in the
texture.
▲ Blood in the urine (hematuria). Approximately half of children with
Polycystic Kidney Disease present microscopic hematuria, and some have
paroxysmal gross hematuria caused by the burst of cyst wall blood vessels. When
kidneys are infected, there will be obvious pyuria, severe hematuria and back
pain accompanied with fever.
▲ High blood pressure (hypertension). This is a common sign of children
Polycystic Kidney Disease. Almost half of patients have high blood pressure
before the serum creatinine increases, which is caused by the stress of cysts on
neighboring tissues, inducing rennin, angiotensin and the response of
aldosterone.
▲ Urinary tract infection. More than half of Polycystic Kidney Disease
patients appear urinary tract infection, and is more prone to women than
men.
Besides, other symptoms also include cysts in other organs, mass in abdomen,
kidney stones and urine protein and do on. Patient should receive effective
treatment to prevent the disease progress into Renal Failure.