Polycystic Kidney Disease (PKD) is a kind of genetic Kidney Disease, belonging to congenital abnormality. This disease usually involves bilateral kidneys with unequal severity. When cysts grow bigger, they will compress healthy kidney tissues, causing renal ischemia and anoxia as well as kidney low perfusion. Then PKD patients may get High Blood Pressure.
Countless cysts spread over whole kidney cortex and kidney medulla, which
make kidney shown as grapelike shape. Some cysts may be connected to each other
but not open to renal pelvis. Cyst pressure on kidney may result in renal
tubular atrophy and sclerosis as well as kidney function decline. Meanwhile,
these cysts also compress kidney blood vessels and sometimes may be accompanied
by renal arterial sclerosis.
Clinically, PKD patients mainly have the symptoms of waist discomforts or
pain, abdominal masses and so on. Kidney internal infection can appear easily.
70% to 75% PKD patients have increased blood pressure which causes headache and
vertigo as well as other symptoms. With cysts growing, they will compress
surrounding kidneys, causing more rennin to be secreted. Then Nephrotic
Hypertension happens. After treatment, some patients can get their blood
pressure normal. However, if patients can not accept proper treatment in time,
their blood pressure will increase continuously, which can lead to heart
enlargement and Heart Failure.
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