2016年7月26日星期二

Urinary Tract Infection Caused by PKD

Urinary tract infection is one of the most common complications in patients with Polycystic Kidney Disease (hereinafter called PKD), which mainly presents Cystitis, Pyelonephritis, Cystic infection and Perinephric Abscess. In clinical symptoms, urinary tract infection usually emerges at first. And 50% to 70% of patients can present once urinary tract infection at least in their whole life and this often occurs in female patients.

Clinical manifestation and imaging checks

PKD patients usually show urgent urination, odynuria and pains in pubic arc area, when they have cystitis. If infection affected upper urinary tract, patients can manifest persistent high fever and lumbago. But it’s hard to give a differential diagnosis between pyelonephritis and cystic infection. To ascertain the disease, some additional tests need to be conducted. If urine cultivation presents positive, the number of leucocyte in blood increase and it has a rapid response to regular anti-infection treatment, pyelonephritis can be diagnosed. If blood cultivation show positive and patients feel local tenderness, patients are probably to suffer from cystic infection.

When PKD patient doubt that they have urinary tract infection, they should take imaging checks. Abdomen AP can indicate stones’ location, size, number and perinephric abscess. CT scanning has a sensitive detection on perinephric abscess. For those patients adjoint urinary tract infection, apparatus checking can increase the incidence of septicemia. Therefore, it is advisable to avoid pelvis radiotherapy backward.


Certainly, if apparatus checking is inevitable, patients should take proper antibiotic to prevent inflammation within 24hrs once checking. And you can email me at kidney-treatment@hotmail.com or consult online for additional informaton about kidney disease.

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