2016年4月7日星期四

Urinary Tract Infection Caused by Polycystic Kidney Disease

Urinary tract infection is a common complication of Polycystic Kidney Disease which includes cystitis, pyelonephritis, cysts infection and perinephric abscess. The primary clinical manifestation is urinary tract infection for about 20% patients with Polycystic Kidney Disease. 50%-70% patients with Polycystic Kidney Disease will present urinary tract infection at least once and the females are more common to present it. It is very difficult to be cured and most of them will develop into perinephric abscess and sepsis. About 1/3 patients with Polycystic Kidney Disease who are under dialysis have the symptom of urinary tract infection. Although they are taking effective antibiotics to prolong the course of treatment, there are still some patients develop into perinephric abscess.

The clinical manifestation and imaging study

When Polycystic Kidney Disease is accompanied with cystitis, the clinical manifestations can be presented as urgent urination, odynuria and pain in bow area. If the infection occurs in urinary tract, the persistent fever and backache may appear. Clinically, it is difficult to differ pyelonephritis from cysts infection. If the urine culture presents to be positive, there is an increase of white blood cells in blood, and reacts quickly to common anti-infection therapy. While, if the blood culture presents to be positive and there is pressing pain in the local area, the cysts might be infected.

When patients with Polycystic Kidney Disease seem to have urinary tract infection, they should take examinations of imaging study and abdominal plain film (AP), through which the location, size, number of urolithiasis and perinephric can be seen. CT scan has a good sensitivity to perinephric abscess, while for those who have get urinary tract infection; the equipment inspection may increase the risk of getting sepsis. Therefore, the retrograde pyelography should be avoided if possible.

Treatment


Shijiazhuang Kidney Disease Hospital adopts the Micro-Chinese Medicine Osmotherapy to treat urinary tract infection, which has achieved remarkable efficacy. It can inactivate the inflammation caused by infection; inhibit the growth of the kidney cysts; repaired the damaged kidney function.

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